- Exam
- NCLEX-RN
- Read time
- 18 min
- Updated
- Jun 2026
Understanding Drug Classifications
Pharmacology questions on the NCLEX-RN test your ability to safely administer medications and recognize adverse effects. Rather than memorizing individual drugs, focus on understanding drug classes and their shared characteristics.
The "Big 6" Drug Classes
These six drug classifications appear most frequently on the NCLEX-RN:
- Cardiovascular drugs — Beta-blockers, ACE inhibitors, calcium channel blockers
- Antibiotics — Penicillins, cephalosporins, fluoroquinolones
- Pain medications — Opioids, NSAIDs, acetaminophen
- Psychotropic drugs — SSRIs, antipsychotics, benzodiazepines
- Endocrine drugs — Insulin, thyroid medications, corticosteroids
- Anticoagulants — Heparin, warfarin, DOACs
Memory Techniques That Work
Use these proven strategies to retain pharmacology information.
The Suffix Method
Drug names often share suffixes that indicate their class:
- -olol = Beta-blockers (metoprolol, atenolol)
- -pril = ACE inhibitors (lisinopril, enalapril)
- -sartan = ARBs (losartan, valsartan)
- -statin = HMG-CoA reductase inhibitors (atorvastatin)
Frequently Asked Questions
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Written by
Emily Hart, RN, BSN· Clinical Nurse Educator
Emily Hart is a registered nurse and clinical nurse educator who turns dense clinical material into clear, exam-ready explanations. She has guided thousands of nursing and nurse-practitioner students through board prep, with a focus on the reasoning behind each answer — not rote memorization.
Last updated · Originally published






